CBS-KNAW fungal biodiversity centre
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Centraalbureau voor Schimmelcultures

Utrecht, The Netherlands

Food mycology

The growth of fungi may result in several kinds of food spoilage: off-flavours, toxins, discolouration, rotting, and formation of pathogenic or allergenic propagules. Over the past 40 years fungi in foods have received special atten-tion because of their ability to produce toxic metabolites. Although some fungi, such as Claviceps purpurea have been known for centuries because of their high and acute toxicity (it was only after the discovery in 1960 of the aflatoxins, carcinogenic metabolites of Aspergillus flavus, that a large number of species were found as mycotoxin producers.More than 400 mycotoxins are known today, aflatoxins being the best known, and the number is increasing rapidly. Mycotoxins are secondary metabolites which are toxic to vertebrate animals when introduced via a natural route. The toxicity of these metabolites is very different, with chronic termed toxicosis being the most important to humans. However, only a few mycotoxins are well described in toxicological terms. The most important toxic effects are different kinds of cancers and immune suppression. Several mycotoxins have a very significant antibiotic activity as well, which in time may give rise to bacteria with a cross-resistance to the most important antibiotics used today, like penicillins.

The presence of potential toxinogenic species on food products does not always mean that these products contain mycotoxins; various environmental factors also play a part. Furthermore, the toxicity of many frequently occurring moulds has not yet been fully investigated and there is often no chemical method available to demonstrate the mycotoxin that may be present.

CBS has experience and expertise in handling mycological problems of food and beverages and can carry out research and surveys.

More information

The institute also has published books and provide courses on indoor fungi.